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KMID : 0191120110260050599
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Journal of Korean Medical Science
2011 Volume.26 No. 5 p.599 ~ p.603
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Long-term Mortality in Adult Orthotopic Heart Transplant Recipients
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Jung Sung-Ho
Kim Jae-Joong
Choo Suk-Jung
Yun Tae-Jin
Chung Cheol-Hyun
Lee Jae-Won
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Abstract
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Heart transplantation is now regarded as the treatment of choice for end-stage heart failure. To improve long-term results of the heart transplantation, we analyzed causes of death relative to time after transplantation. A total of 201 consecutive patients, 154 (76.6%) males, aged ≥ 17 yr underwent heart transplantation between November 1992 and December 2008. Mean ages of recipients and donors were 42.8 ± 12.4 and 29.8 ± 9.6 yr, respectively. The bicaval anastomosis technique was used since 1999. Mean follow up duration was 6.5 ± 4.4 yr. Two patients (1%) died in-hospital due to sepsis caused by infection. Late death occurred in 39 patients (19.4%) with the most common cause being sepsis due to infection. The 1-, 5-, and 10-yr survival rates in these patients were 95.5% ± 1.5%, 86.9% ± 2.6%, and 73.5% ± 4.1%, respectively. The surgical results of heart transplantation in adults were excellent, with late mortality due primarily to infection, malignancy, and rejection. Cardiac deaths related to cardiac allograft vasculopathy were very rare.
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KEYWORD
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Transplantation, Heart, Death
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